Hi Amanda -Wanderstar is correct when she says some people cannot tolerate the SSRIs. I am one of those people. I was given Paxil for anxiety and after losing a weekend to the side effects (anxiety worse than before, D like water, not being able to stay awake longer than an hour at a time, etc) I decided that this was not for me. I think the key phrase in Joaniemama's post is "tolerable" side effects. If you cannot function, then it is time to look for something else. I found the tricyclic family to work best for me. I was on impramine (Tofranil). It helps with depression and anxiety. But, best of all, it help with the D and cramping. Because I am currently trying to get pregnant, I cannot take impramine. The doctor has me on Welbutrin for depression and BuSpar for anxiety. I've been told that BuSpar is an older "formula" (for lack of better word) SSRI and less potent than the current ones. Welbutrin is slightly constipating and you can get D with BuSpar, so they balance each other.Whatever you decide to take, go with the lowest possible dosage and work up to the recommended dosage. You may not even have to go that far. I'm taking half the recommended dosage of both of the medications. Anything more causes intolerable side effects. Talk with your doctor, tell them what you are feeling and don't let them intimidate you. That was my mistake with the Paxil. My doctor said cut the dosage and give it time. I was so out of whack by day 4 that I finally said Enough! Yes, these meds take a while to work, but you should not have to suffer from side effects when there are other things available.