Stargazer, I also am a newbie...just registered! Was so glad to be given the url to this site by a friend indeed! In answer to your query, I was very young when I first had symptoms of IBS...of course it has been called many things over the years...but it is still IBS. When I got into my teens, all symptoms stopped. I had no more trouble until after having my son at age 23, then they were minor. At the age of 32...the dam broke and my problems began again. As I have aged..I am now 52...things have progressively gotten worse until this past spring when I literaly became homebound. I lost a great deal of weight and became very weak. I found a new doctor and it was decided I was a prime candidate for lotronex, as my symptoms, diarrhea, pain, and spasms were a daily thing by now. I started it in August and took my last pill last night. Needless to say, I am desperately searching for SOMETHING out there that will make life easier for me. I have tried it all, and nothing seems to work. I have not worked for the last 10 years because of IBS and the ensuing depression. On the lotronex...I lived a totally normal life. The only side effect that I "suffered" was that I was able to stop my paxil for the depression! Don't loose hope about your dream to teach. Keep searching...and the drug companies will keep researching and maybe.....there is always hope!!~Pat~