Denny, Hope you find something that works for you soon. My Son has changed meds, too. He's doing really well on Remeron. He sounds like his 'ol self again!!! His last attempt was with Celexa. His counselor told him that he was one of those "rare" individuals to have an adverse reaction to Celexa, but he did. He seems ultra-sensitive to most meds. Just like me!!! The counselor also told him that a person who is hyper and anxious should never be given an SSRI -- it works against them rather than for them. Anyway, hope you can find something that works well for you. Hang in there. Karen