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My GI doc told me that I have IBS and GERD, and that they will aggravate each other. He also said that treatments for one part of the gut may flare up another part. So, if I take, say, a PPI for the GERD it will aggravate the D side of the IBS. Some antacids made of calcium totally swing me to the C side. It's a vicious cycle sometimes.
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