That sounds like an awfully large dose. I'm taking Colestid (the pill form of Questran) but only take 2 grams in the morning and 2 at dinnertime.Are you taking it for IBS/D or do you have bile salt diarrhea (from gall bladder disease)?I had my GB removed a few years ago and have had terrible bile salt D since then. The Colestid helps manage it pretty much.