Okay,I'll share, but I'm really afraid of jinxing my good luck...... I have been taking Cholestyramine for just over a week. (another name for Questran) I take one packet mixed with water each AM. (I'll warn you, it tastes awful, but I don't care! I'd eat dirt if it will work!)So far, so great! I came right out and asked my doctor if there were any meds that actually WORKED for IBS, or if I would just have to try 1,000 things that never really helped. (I have tried Lotronex and Calcium without much help) He told me that he has lots of IBS patients having good results with Cholestyramine! It's cheap ($10/2 months with insurance and it's my understanding that you can take it while pregnant since it is really just a binding resin and not actually absorbed by the body)So, give it a try! Here's hoping for continued success.....morning