To Debcantgo or anyone else with the problem,I have colonic inertia , irritable bowel syndrome, and pelvic floor syndrome. I know the stool eventually gets to the sigmoid colon. I got hooked on senna products which really upset me because in the past, MOM and Miralax helped me. Now Miralax and Amitiza work for a short time and then blows me up and gives me pain. Senna products and I tried Ducolax for the first time will work, but I get such excruciating pain after a bowel movement, I feel like I could die. Pain is more of an issue for me then anything else. I get pain whether I go or don't. The pain is actually worse after a bowel movement. When this happens, I can't eat as eating makes the pain worse. I have tried so many different diets and nothing has worked. I can eat one thing one day and be okay and be fine and then eat the same thing the next day maybe after having a bowel movement and have a huge amount of pain. Does anyone else have this problem? The pain gets really bad a few hours after dinner and now lately it can start about 1am and wake me up from a dead sleep. I know I have psychological issues, but would that wake you up with pain from a good sleep? I am losing a lot of weight and all the doctors say is, "you have to eat". I was up last night until 5am. If I skip dinner, I have less pain. I also take pain meds which I know is bad, but I still have bowel movement even with the pain meds. I try so hard not to take them, but my pain is so excruciating, that I can't stop myself. I feel like I'm starving to death. I did feel better when I took the Miralax, Zelnorm and the Amitza for a short while until they blew me up and gave me pain. The Zelnorm just stopped working. Someone suggested Magnesium Citrate powder, something called Nature's Calm. It works if I take 2 tablespoons, but it gives me bad cramps and really blows me up. The person who reccommended it said, it's because the stool is pulling away from the walls of the intestine.Also, the pain has changed. It used to be more on my lower left side and left side, but now its in my lower abdomen, and it presses on my bladder causing me to either have urinary frequency or burning and I don't have an infection.Any suggestions. I think if I keep on going on this way, I will die. Thanks for listening.