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i use it before bed it works better for me but it can work diffrent from person to person i can tell just by how my stomach reacks to just after eating dinner if it starts making noises after dinner then i might take the imodium then other wise if it dont then i take it before bed so when i wake in the morning i dont have the urge to have to go right upon waking.
 

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I take a small dose before bed and a full dose immediately upon wakening. I still want to have a BM to sort of empty out before leaving the house. If I leave the house without going I can almost bet it’s coming out in an hour or two anyway.
 
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