Hi Everyone.I just wanted to pass on this information, to hopefully help any of you that have similar stories to mine. I have had IBS with awful pain and diarrhea for over 18 years. I've seen numerous consultants and had all the usual tests and been told to get on with it and take Codeine Phosphate to control the pain. I'd typically go about an average of 9 times a day and feel constantly tired.About a year ago I went back to my GP again following a really bad 6 months and he referred me to an IBS center of research in Withington, Manchester, U. I tried every tablet going to control my IBS (including each brand of antispasmodics and low dose anti-depressants) and had a whole new set of tests done. Still nothing worked!I fortunately saw a a doctor who sent me for a nuclear medicine abdominal scan (SeHCAT Test) and it turns out I have not got IBS-D but I have BILE SALT MAL-ABSORBTION. Because I don't absorb my bile salts they leak into my large intestine and cause pain and diarrhea. My consultant was really shocked as I have no history of surgery on my bowel or my gall bladder. I have now had my first month of Questran Sachets and have not had any diarrhea for the first time in 18 years. I can't tell you how blissful it is to have my life back and not be running to the loo all day. Also to have some sort of medical answer.Apparently it's quite rare to have it, but with so many people being diagnosed with IBS I'm wondering if it's not more common that the doctors think? Do get in touch if anyone would like any more information. Good luck.