Anyone else out there convinced that these are related serotonin-dependent conditions? I found that taking my migraine medication: Amerge (or any of the triptans) will precipitate a colitis (pain) attack, and taking say, Librax, will precipitate a migraine. I have IBS-D which has gotten consistently worse over the years and I'm starting to wonder if there's something out there that would prevent both. Anyone played around with this idea and found something that works well for both problems? I've been looking at 5-HTP as a migraine preventative, but wondered if it wouldn't end up making the IBS much worse. Thoughts??