I'm 43, male. I've suffered from IBS-C for about 14 years now. Have tried various medications and diets to no avail.My bouts of IBS-C flare up intermittently and cause me a great deal of pain and discomfort. One thing I have noticed though is that stress/stressful thoughts causes gurgling in my guts and very bad, momentary spasms of pain.Relaxing helps of course, but this is by no means easy when you're in a lot of discomfort.Are there yet any medications which would help to suppress the link between brain activity and the gut? I'm sure this would help matters an awful lot.