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I saw an ad in the Cleveland Plain Dealer for an IBS-D study for females only (I'm a male and can't participate - but I did not call them) in Ohio. It states women have to be 18 and over and have IBS for at least 6 months. It's a medication study but doesn't state which med.The company is Ohio Clinical Research, LCC (not sure where that is) and the number is (440) 684-8900.