Could there possibly be a link between anitdepressant withdrawals and IBS in some people? I have heard that some people are advised to take small doses or Paxil to help with IBS. But can those same drugs trigger IBS? I took Paxil for two years, never having a problem with IBS or anything like that. It took me 9 months to wean off of it(the withdrawals are HORRIBLE!), and I completely quit taking it about a month ago. That very week I started noticing some C, and soon afterwards I started having full-blown symptoms or IBS-C, including abdominal discomfort, my abdomen feeling like i just did like 200 sit-ups, bloating(haven't noticed any distension really), altered stool frequency and consistency, frequent grumbling, LOTS of gas production(but it almost NEVER smells even remotely bad), but no bleeding or anything like that. However, I'm miserable! This all happened right after completely ceasing the Paxil. Paxil is a SSRI, and messes with the reabsorption(sp?) of seratonin in the synapses. I was told that seratonin was also the neurotransmitter responsible for triggering muscle contractions in the intestines. Paxil has particularly severe withdrawal symptoms(i'm sure you've heard about it on the news). Also, a friend of mine told me that she had experienced the same thing after quitting paxil. She said her IBS lasted for a few months and then went away. I went to the DR once and he didn't seem too concerned, gave me an antispasmodic that now seems to be giving me MORE C. Plus I'm on Zyban to quit smoking, which says it can ALSO cause some C. What's a poor 21 year old guy supposed to do?any idears?