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I've been on the net for a few hours today and happy to know I'm not alone with IBS and all the related difficulties - staying at home most of the time, fears of public embarrasment etc. I'm hoping to get some guidance, and I'd be grateful for any advice or tips. I have a fissure-in-ano, very painful over period of 18 months, with IBS, but since January this year I've had chronic diarrhea. I've had a couple of sigy's and barium en's, and tested negative for coeliac as I've lost about 20lbs, so the consultant is putting it down to IBS. I may need to have surgery for the fissure - is there any alternative? Are fissure commonly linked to IBS? I'm currently prescribed Mebeverine (Colofac) tablets, but there's no impact yet after 3 wks. Hope to hear from someone soon, regards, Drummeg