Being what I am it is hard to assign a numerical score....I will be happy to state my experience. I have used IBSACOL alone and in combination with another immunomodulator (not currently available in the USA) for I think about a year.I will say that I am a sufferer of severe cell mediated hypersensitivity reactions to foods and chemicals. This problem, which affects primairly diarrheic IBS victims, is called "loss of oral tolerance" by immunologists and allergists who are expert in this area. It is these types of reactions, and mucosal immune response as well as can be seen in true allergy and pseudoallergy, which substances of the type in IBSACOL should blunt.My experience has been that I have regained sufficient oral tolerance as to be plainly noticeable. I have been able to reintroduce certain foods into my diet which I had NO tolerance for at all for many years. This is good enough for me to keep popping the capsules each day. Hey Dianne, guess I would say THANKS that I can eat pizza again at least once every week with NO symptoms whatsoever...and I now eat wheat daily with no reaction. No Tiajuana Two Step from the Pies (EXCEPT Dominoes...no matter what I do or what measures I take, there is something in Dominoes sauce which I will NEVER BE ABLE to tolerate...all others are now GO)..even that DiGiorno Gar-bage out of the frozen food section (just like delivery...yeah right...)These were two intolerances which caused me great dietary consternation.I would not discourage anyone with food or additive provoked IBS symptoms (and there are a lot of you) from trying a course of IBSACOL.The literature supports the probable efficacy of the substances in IBSACOL for modulation of immune response.The only cautionary note I would even consider interjecting is for anyone who has a presentation consistent with any infective gastroenteritis or dysbiosis induced loss of tolerance.Immunomodulation should be approached with caution until one has eradicated any possible infection in the gut, or if dysbosis is suspected a good quality probiotic (multistrain) course should be followed first and the results noted.Other than that I personally have seen nothing in the literature nor among patients I know who have attempted IBSacol which would cause me to dissuade anyone from trying it. The odds are that it will improve oral tolerance...the degree will vary from person to person but there is as yet no way to know what that will be without a trial. At least 30 days should be tried I would opine.Now excuse me because it so happens today is Pizza day and I need to go swallow some capsules one hour PP (PrePie).
At this point (nearly four weeks of use), I would rate it at 9.Within a few days, I felt relief from urgency and bloating and a reduction in daily episodes of D. After one week, I'd gone from D to loose stools, and the next week was experiencing normal bowel movements (2-3 a day, down from about 8-10 episodes of D a day). I am now eating several foods I was avoiding including salads, broccoli, and tomatoes in small quantities.A bonus I hadn't expected is that I am also sleeping better -- this is unconnected to IBS symptoms as they have never been a cause for sleeplessness. I can only assume that this supplement may influence nerve chemistry is some subtle way.Truly, Ibsacol has improved the quality of my life and I will certainly reorder.
I tried it a few months ago for a period of about 10 weeks taking 4 caps 3x daily. To be honest i noticed no difference whatsoever except for perhaps a bit of hope that I might get something out of them with time. Perhaps I didn't give it long enough. But please don't go by this, it looks as though other respnses have been successful and everyone is different. Good luck, Midwinter maddness
COLDWEATHERYeah, Just like not all asthmatics respond to certain immunodulatig drugs, not all IBS victims will respond to OTC immunomodulation, that's all. However that does not mean you are stuck as there are other things to pursue. I suggest a copy of this book for your nightstan...it might help youIBS: A DOCTORS PLAN FOR CHRONIC DIGESTIVE TROUBLESBy Gerard Guillory, M.D.; Vanessa Ameen, M.D.; Paul Donovan, M.D.; Jack Martin, Ph.D. http://www.amazon.com/exec/obidos/ASIN/088...3369143-6824157 MNL
my IBS causes me to get lousy sleep. even though i don't have trouble falling asleep, it will always cause some type of unrestfull sleep.if i ever have a healthy bowel movement in the morning then it almost always corresponds with very restful sleep. therefore, i can omly conclude that my IBS is somehow or another intimately connected with my sleep chemicals.afterall, everything is connected and related.i am going to try ibsacol because i know my immune system is involved because i have food reactions.
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