My psychologist recommended that I take Zoloft for anxiety and depression. So I went to my doctor and got some, but I didn't start taking it, because a few days later I had an appointment with my GI guy. He told me not to take the Zoloft because it'd make IBS symptoms worse. Then the GI guy gave me IMIPRAMINE. He said it was suppose to be like a miracle drug. And, all the reading that I've done talks about it being an anti-depressant and what not, but what makes it a miracle drug for IBS? I don't understand...Does anyone have information? Or miracle stories? Thanks!!