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In my case indigestion was my first problem, including some kind of "Oh my God, I must have an ulcer!" gastric attack. Later, the diarrhea developed. In the last couple of years of that the indigestion became much, much worse until it lasted all day long as a burning across my abdomen. Finally, I began refluxing at night. As far as I can tell, some level of inflammation was at the root of it, no doubt caused by years of chain smoking. (This continued on for another 5 years after I quit smoking.) In 1998 I began taking a flavonoid supplement to control my cholesterol deposits and within 2 months, the indigestion stopped, after about a year the D stopped, and I never refluxed again. I have not had more than a passing case of normal heartburn or indigestion in almost 12 years.Mark
 
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