I'm at a point now the only meds I am on is NuLevand Immodium for about a week. Nothing my Doc prescribed was working so he told me to try the immodium. The last two months now I have had this incredible fatigue in the morning at work. I thought it was from the meds but now I'm not on any and I am barely able to keep my eyes open. Is this another wonderful symptom of IBS or should I check with my Doc about looking into something else? I actually struggle to stay awake. Oddly enough, I don't have the usual IBS flair-ups over the weekend that I do during the week at work. I can't remember the last time I went through an entire day feeling good.