Now that's interesting, Mike! You mean they're at least TRYING to find out what causes IBS? You're right; all they have rigth now is palliative therapies. As with cancer, I don't think they'll be a definitive "cure" until they know exactly what the cause is.Flux, exactly what are the Rome II criteria? (Provide a link!) My understanding is it mostly involves negative criteria, as in ruling out other possible causes of similar symptoms. In fact, most symptoms of IBS can be subsets of other diseases such as UC and Crohns. I also disagree about the rarity of other, undiscovered causes--during my nearly 2 years on this BB, I've seen members diagnosed with a number of conditions that could be the cause of or contribute to their IBS, including endometriosis, gynecological cancers, gallbladder disease, thyroid disorders, c difficile infection and, in my case, mixed connective tissue disorder. And surely you don't think that researchers have already corectly discovered and named every disease that presently exists?