Hello,I went to a clinical nutritionist who convinced me to first try Flaxseed which did not work then the Probiotics in which I ordered the KE-99. I believe in Probiotics but the KE-99 strain is one of the strongest on the market and did not work for me. I tried the normal dosage for 3 weeks and then scaled back to half the dose for 10 days and was having lots of addl abdominal pain. I did notice a increase in bowel movements but the side effects pain was to much to bear so I discontinued. If taking this, I would start out with half the dosage and then gradually increase. I think everyones body reacts differently in regards to any type of digestive enzyme. Also check out the web site for the KE-99. Good Luck, if you have any addl questions, feel free to email me. Have been living with this ????? for 4 years and education and patience is the key. Ross