I have been suffering with IBS-D for the past 14 years and I recently came off of Elavil after 7 years for IBS-D due to the side effects (some hair loss, overheating, increased sunburn, and major weight gain.) I was taking 20 mg/day and I have now been off of it for a month now and I'm feeling pretty good. However I'm still having some panic attacks/anxiety when travelling so my doctor started me on Klonopin (1 mg/day) for anxiety issues associated with my D. I was wondering if anyone else has had any weight gain while taking this med? I have begun losing the 20 lbs that I gained from the elavil and my heart rate is finally in the normal range. I really want to avoid that same spiral. Really worried about the whole weight thing too. Please help. Any advice will be greatly appreciated!Thanks?