the reason dr' stop refilling is this stuff is a derivative of morphine.......it can become addictive........lomitil is suppose to b used only occasionally...........i use to use it, but it doesn't cure anything.........it is a quick fix that doesn't last.........read my other posts & u can find out how i CURED myself.........it has been amazing.........also, the D is a result of adrenals gone weird........it's a complicated thing & so many things influence it.......look up & research all the things that come into play.........u may b low in tryptophan, adrenal hormones, sodium, potassium..........anything can put u on the road to this horrible thing & it didn't just start, it came about over a period of time........