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quote:irritable bowel disappointment [top] A new treatment for irritable bowel syndrome (IBS) will not now be introduced in the UK, after its withdrawal in the USA on safety grounds. Lotronex � a drug developed by GlaxoWellcome for the treatment of women with diarrhoea-predominant IBS � had been available in the USA since February 2000. About half a million prescriptions have been written for it. But following reports of severe gastrointestinal problems associated with the product, including five deaths, the manufacturers were asked to withdraw the product by the US licensing authorities. The company has since decided to withdraw licence applications for Lotronex worldwide, a move which will include the UK. IBS, which generally includes unexplained bouts of diarrhoea or constipation, stomach pain and wind, is notoriously difficult to treat. Other drugs are in the pipeline but, with the demise of Lotronex, IBS sufferers will have to continue to rely on dietary changes and stress control to relieve their symptoms.
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