Hello Jefferey,I am a 28 year old female Canadian who is participating in a study on Lontronex. The protocol is mandatory before they approve any new drug as you may already know.I have been on Lontronex for just over a week and have a bit disappointed by the results. I have not experienced adequate relief from symptoms but I have heard that maximum effect may take up to 3 weeks. I have experienced stomach upset and headache.Please let me know if there is any other information you are looking for - I would be happy to help.Brittany