Hello Jefferey,I am a 28 year old female Canadian who is participating in a study on Lontronex. The protocol is mandatory before they approve any new drug as you may already know.I have been on Lontronex for just over a week and have a bit disappointed by the results. I have not experienced adequate relief from symptoms but I have heard that maximum effect may take up to 3 weeks. I have experienced stomach upset and headache.Please let me know if there is any other information you are looking for - I would be happy to help.Brittany
Looking for any Canadians who have tried Lotronex
I am curious to know if there are any Canadians who have tried Lotronex. Perhaps you picked some up on a visit to the US...Lotronex approval is before the Canadian authorities and there is an opportunity for us to keep them abreast of how Canadians have fared with it.Jeff
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Brittany,How do you know in your study if you are on Lotronex or a placebo?Maggieanne,It looks like Lotronex will not be available until early 2001 in Canada.
G
Hi Jeffrey,In the first phase of the study, people are weaned off any gastrointestinal medication they are taking immodiume, pepto bismal etc.Then all participants are given Lontronex. Their progress is monitored. After 3 months, only "responders" will continue with the study. These are people who have responded to the medication and have had a decrease in symptoms. In the 3rd phase of the study, the responders are separated into two groups. One group will recieve a placebo and the other will recieve Lontronex. This is the most important part of the study. The group that receives the placebo should have a return of symptoms in one week. This is how they explained the mechanics of the study to me and what I agreed to.Lontronex will probably not be avaialable until 2001 pending these mandatory clinical trials.Brittany
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