Lotronex Info

I think you are misstaken. The old lotronex was always a 1mg pill, taken TWICE a day. New pill is the same 1mg, but taken only once a day. Bill

I could be wrong but I thought the old pills were 2mg pills which I took 2 times per day. I distinctly recall 4 mgs per day was prescribed but that I cut back at times. I did know about the doage and it's worrying me that it may not be enough. We'll see. Also, how do you get the stickers? I thought the Dr. got the stickers?

Nope, not misstaken. My GI told me so. I couldn't remember so I searched on Glaxo & yes, the original pills were indeed 2 mgs daily.

I'll have to check but I thought the new dose was 1 mg once a day INITIALLY and once you see how that goes it goes up to 1 mg 2X a day which is down from the full 2 mg up to 2X a day from the original dosage.But I will have to see if I can find this, rather than pulling it out of my fuzzy headHere is the current dosing, which is one tablet initally going up to 2 a day if needed

quote: Begin with 1�tablet a day for 4�weeks to see how LOTRONEX affects you.Although the effect of 1�tablet a day on IBS symptoms has not been studied in clinical trials, you and your doctor may decide that you should keep taking this dose if it adequately controls your IBS symptoms and you have not become constipated or had ischemic colitis while taking LOTRONEX.* If you try 1 tablet a day for 4�weeks and it does not control your symptoms, does not make you constipated, and does not give you ischemic colitis, tell your doctor. Your doctor may tell you to take 1�tablet 2 times a day, the dose that was used in clinical trials.If 1 tablet 2 times a day does not work after 4�weeks, LOTRONEX is not likely to help you and you should stop using it and call your doctor. http://www.fda.gov/cder/drug/infopage/lotr...guide060502.htm

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Now I can't seem to find any of the old prescribing info that I can verify was pre the re-release.However it seems to me that most people that remember taking it before remember 2 mg pills...but memory is a funny thing.K.

I have my old blue bottle of Lotronex (with 1 pill still inside for a rainy day). Anyway, it says LOTRONEX TAB 1MG (BLUE). The directions are: Take one tablet twice daily.

That's weird, because I am sure I took 2mg twice a day before. Can't forget that little blue wonder.Jeremy

Hi,They were 1mg. I still have them for rainy day too.

That's right, they were 1mg twice a day. I still have one of the old bottles.

How weird is this?! Can this be right? I called Glaxo and asked them what the "old" Lotronex mg was. The Lotronex Specialist told me that the "old" Lotronex came in TWO strengths 1mg and 2 mg. Now they only have 1 mg. only. I never heard of that? I thought all Lotronex was the same strength?

OK, now I called my old pharmacist she said that my prescription was always 1mg.I guess my GI and the Glaxo Lotronex Specialist are wrong. Who would have guessed?

My GI apologized to me. He did forget. The Lotronex Specialist...uh well, I think she needs a different position.

There were 2 doses, 1mg and 2mg.

I think the 2 mg pills were only used in the clinical trials, so any of you who were in the trials may have had 2 mg pills. However, these were never available commercially and those of us who weren't in trials were prescribed 1 mg twice a day. Among the 8 studies GSK has committed to doing this time around are a few that test different doses, but none higher than 2 mg per day. It seems they are looking to establish the smallest effective dose for the most people. Of course we are all different, but don't look for 2 mg pills. All they are making now is 1 mg. (in fact, if I remember correctly from the advisory committee meeting in April GSK said it would be prohibitively expensive to make any but the 1 mg pills for which all their equipment was set up). Please, let's all play by the rules so that Lotronex stays on the market this time around. The rules are NOT that hard to follow.

I agree Julia...we MUST play by the rules this time or we risk losing Lotronex again. For example...Faxed or mailed rx's are not permitted! Prescriptions ARE NOT to be written for more than 30 tabs initially WITH NO REFILLS!Refills must also have a sticker!PLEASE stick to the rules! For ALL our sakes!