I have had IBS/D for 8 years. It is better during pregnancy, but usually comes back shortly after. My son is now 5 months old and I have gone back to work. The D is back. I had to leave work at 10:00 am, mornings are the worst! I have several months stock of Lotronex that I am desperate to start taking again, but I don't know what affects it could have on nursing. Any advice or comments. Thanks!