Hi Kendra. I have been on Lotronex since April and I had mostly very soft stools and D and could go all day. Just this past 2/3 weeks I have been constipated. Just found out today that in order for me to have my Lotronex covered my Dr. had to call in and get a precertification so that Ins. will pay. I was surprised that they just started this now!! Hopefully you will start to feel better and the Insurance co's will realize how important a med this is. Good luck . I'll be looking for you follow ups.------------------