So I've found websites that tell me that low dose antidepressants are beneficial for IBS-D. It seems that 'low dose' is 10mg on tricyclics. But I'm now on 30mg and it still doesn't control my diarrhoea when I get bad 'flare up'. 75mg is the dose for those with depression and I don't want to take that much as I'm not depressed! Does anyone have any further info on this? Anyone found tricyclic antidepressants help with the diarrhoea?