Hi K,Hope you can help shead some light about a situation I am in. I have severe motility problems and possibly colonic inertia. I have also been using irritant laxatives which I am unable to stop using without my colon shutting down completely. I have not responded to any of the fiber or osmotic laxatives due to lack of muscle contraction in my colon. I also have severe abdominal pain 24/7 mainly on the LRQ and there is continually a feeling of obstruction in that area and a bit on the left. I have not symptoms of problems in the rectal/anal areas... no discomfort, pain, blockage, pressure or build up.I am confused why doctors are so concerned in performing the above tests as priority and what the relevance would be in motility disorders, especially in my situation. I had a Manometry 9 months ago and it was abnormal and they did nothing about it. Now another doc wants to redo it plus perform a defocography. I dont understand the relevancy of this and am really concerned. Also, what can be done if they do find abnormalities and how would this tie up with the pain motility issue.I also have suspected diffuse ileus, ischemic colon, abnormal loop of bowel, ganglion cells, edema and fibrosis in the lamina propria. Colitis is suspected.I cant understand why this would not be further investigated and dealt with instead of the above tests.It would really help me cope with everything going on if I had more information and would sincerely appreciate any information or feedback you may have.Many thanks.