I have been visiting my regular doctor every three weeks and the GI every six weeks. Between the three of us we are trying different meds to see what works best for me. I am currently taking Lomotil for the D), Paxil (for the anxiety), and after reading people's successes with calcium supplements I bought Os Cal (haven't started that yet). The paxil doesn't seem to be doing anything, and I try to take the Lomotil only if I have to go out (which I try to avoid leaving the house at all costs). It makes me constipated the next day though. Has anyone had any experience with any of these? I asked my doc about the calcium and he said that he had not heard of that helping D. I figured at this point I am willing to try anything. What has worked best for people? I need to be able to do things away from the house in the summer. I am sick of being stuck in the house. I need serious help!!