yes that is correct. MSM (methyl sulfonyl methane)gave me 3 1/2 months of almost symptom free relief. that was after 20 years of uninterrupted suffering from cramping, bloating and constipation. I also had to eliminate sugar and cut back on carbs but the MSM was the UNMISTAKEABLE component to my recovery. now the bad news. i had to quit taking it (15 grams/day) because it caused a horrible bout of anxiety, energy (which had an upside), insomnia, and eventually depression. my theory is that it increased my methionine levels and therefore my adrenalin levels through the roof which also caused a severe drop in my histidine/histamine levels. the loss of histamine may be the cause of the anxiety and insomnia which escalated into a full blown depression. i also think it dropped my serotonin levels (prozac went from 2mg. to 20 mg.)fortunately i was able to quickly reverse it by stopping the MSM and taking some 5-HTP (quit the prozac) and some N-acetyl-L-tyrosine. now i am once again hopeless -- I knew it was too good to be true. this curse will be the death of me yet.