Hello everyone, I only found this site last week and find it very comforting to know that I'm not the only one with this unresolved constipation problem. For years, I've spend thousands of dollars trying everything to no avail. I'm 41 years old and this constipation has always been part of my life. I always ate lots of fruits and vegetable (I'm semi vegetarian), chicken, fish, a bit of red meat, etc. Once in awhile I'll have a junk food feast but it's not often (once every few months). Lately I was seeing a homeopath that helped me somewhat but like everything else I've ever tried it's effect was starting to fizzle and not work anymore. He believed that my hormones was the culprit because a few days before my period and during my period I would completely shut down, nothing would work. He tried a few times to stimulate my hormones and I would completely shut down also. Anyways, I saw this article in last weeks paper about Zelnorm. It sounded terrific!! They talked about how it affects the hormones in the gut and how the results were very good with hardly any side affects. Three days ago I got a prescription and started with my first pill on Tueday night. Wednesday morning I had diarrhea! Not bad diarrhea, just once and it was over. It actually felt terrific since I hadn't gone in over 4 days. I have to mention also that this was 4 days before my period when I usually start to really shut down. The second day on Zelnorm I also had diarrhea, twice! Wow I'm amazed!!! This might be the answer to my problem. And again this is not diarrhea that I have to rush to the bathroom or else. I just feel an urge, go to the bathroom and it comes out as diarrhea. I'm writing this Friday morning, the day before my period. I feel a bit of period pains ... I know I'll be starting later tonight or tomorrow and I just had the most wonderful bowel movement!! This morning it wasn't diarrhea. It was a well formed, a bit loose still but altogether. I'm totally amazed and so excited. I think you should all do yourself a favor and try this new drug, especially if a change in diet does nothing for your constipation. I was one of the ones that if I had more fiber I would get really bad. People have told me often that if they ate like me they would go 3 times a day, no problem! By the way, another great thing about this is the bloating is just about gone. I'm a little bloated still but I think this bloating has to do with my period. I'm really excited and just had to tell everyone! I'll keep you posted.