I thought I'd post a thread of my expereinces, rather than random bits in different threads. I'll keep this short, so you don't have to sift through too much BS.I was never tested for bacterial overgrowth. I live in an extremely rural area, and I was able to get my local doctor to read Dr. Pimentel's book and proceed with the regimen (minus the breath test). I was diagnosed and treated for colitis (caused by a bacterial infection) prior to my troubles with IBS. I feel fairly confident in thinking that the bacteria in my lower colon that caused the colitis probably traveled into my small intestine.I was prescribed Xifaxan for 10 days (1200mg per day). After the 10 days, I felt my symptoms improved 50% to 70%. It's hard to say exactly. Diarhea was always my my main symtom, and for the first time in many years I have only gone to the bathroom once a day. However, I still have about 50% of the gas and bloating that I usually do in the mornings.Because the Xifaxan alone didn't improve my symptoms to 90% or better, I have now started neomycin (1500mg per day) and Xifaxan (1200mg per day). If the combination works wonders, I'll proceed to Zelnorm once a day.I'll keep everybody posted.