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Discussion Starter · #6 ·
Cool is'nt it?
 

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Discussion Starter · #7 ·
Cool is'nt it?
 

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Discussion Starter · #10 ·
I still try to find the maker of this device.Who can help?If the results are so dramatics,i'm ready to take the chance.
 

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Discussion Starter · #11 ·
I still try to find the maker of this device.Who can help?If the results are so dramatics,i'm ready to take the chance.
 

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Um...did you read the materials and methods section??They list the manufacturer of the pacemaker. They are required to do that in scientific papers. This information is usually in the Materials and Methods Section.Prevail, Medtronic, Minneapolis, Minn USA.I don't know if a person off the street can buy one and you would need a doctor to implant it.K.
 

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Um...did you read the materials and methods section??They list the manufacturer of the pacemaker. They are required to do that in scientific papers. This information is usually in the Materials and Methods Section.Prevail, Medtronic, Minneapolis, Minn USA.I don't know if a person off the street can buy one and you would need a doctor to implant it.K.
 

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Discussion Starter · #16 ·
MY RESEARCH STARTED WITH THIS ABSTACT: http://www.bioscience.org/2003/v8/b/989/fulltext.htm Frontiers in Bioscience 8, b1-5, January 1, 2003] COLONIC PACING IN THE TREATMENT OF PATIENTS WITH IRRITABLE BOWEL SYNDROME: TECHNIQUE AND RESULTS Ahmed Shafik 1, Olfat El-Sibai 2, Ali A. Shafik 3, Ismail Ahmed 3 1 Professor and Chairman, Department of Surgery and Experimental Research, Faculty of Medicine, Cairo University, Cairo, 2 Professor and Chairman, Department of Surgery, Faculty of Medicine, Menoufia University, Shebin El-Kom, 3Lecturer in Surgery, Department of Surgery and Experimental Research, Faculty of Medicine, Cairo University, Cairo, Egypt TABLE OF CONTENTS 1. Abstract 2. Introduction 3. Material and methods 3.1. Subjects 3.2. Methods 3.2.1. Pacemaker application 3.2.2. Determination of the myoelectric activity: basal and during pacing 3.2.3. Home pacing4. Results and Discussion 4.1. Effect of colonic pacing on the clinical manifestations of the IBS 5. Acknowledgment 6. References 1. ABSTRACT The treatment of the irritable bowel syndrome (IBS) is not entirely satisfactory as the exact cause of the condition has not been revealed. We have demonstrated in a recent study that the IBS exhibited a "tachyarrhythmic" electromyographic pattern; the wave rhythm was irregular and wave variables were higher than those of the healthy volunteers. We suggested that a disorder of the colonic pacemaker discharges these abnormal waves thereby causing the motor disorders of IBS. In another study, we determined the colonic pacing parameters needed to modulate the disordered pacemaker. In the current communication we investigated the effect of colonic pacing, using these parameters, on the EMG activity of the sigmoid colon (SC) and on the clinical manifestations of patients with IBS. A pacemaker was implanted in a subcutaneous pocket in the inguinal area and its two leads were hooked to the colosigmoid junction. The effect of colonic pacing on the SC EMG activity was investigated by inserting two recording electrodes into the SC muscle. The patients were then trained for home pacing after removal of the 2 recording electrodes. Nine patients (age 42.7�4.2 years, 6 women) with IBS were studied. The pre-pacing tachyarrhythmic pattern of EMG was recorded. On colonic pacing, the slow wave rhythm became regular and wave variables were normalized; the symptoms of the IBS improved. The optimal parameters used for pacing comprised an amplitude of 6 mA, a pulse width of 150 ms and a frequency of 25% higher than that of the basal colonic waves. In 7/9 patients the improvement of symptoms continued when pacing was ceased after 6 months of daily pacing; the pacemaker was removed after 3 months of non-pacing. In 2/9 patients, pacing needed to be continued because the symptoms recurred each time the pacing was ceased. In conclusion, colonic pacing succeeded in normalizing the tachyarrhythmic pattern and relieving the symptoms of the IBS. No complications were encountered and the method was well accepted and tolerated. Further studies on a large group of patients are required.--------------------------------------------------------------------------------From: canada | Registered: May 2002 | IP: Logged | spasman Very Prolific Member Member # 12277 posted 08-21-2004 08:37 PM --------------------------------------------------------------------------------IS THERE ANYONE WHO KNOWS WHICH COMPANY SELL THE COLONIC PACEMAKER?I THINK I NEED AN ELECTRICITY modulator.--------------------------------------------------------------------------------From: canada | Registered: May 2002 | IP: Logged | spasman Very Prolific Member Member # 12277 posted 08-21-2004 09:09 PM -------------------------------------------------------------------------------- http://bioinformatics.weizmann.ac.il:3456/...8/b/989/pdf.pdf --------------------------------------------------------------------------------From: canada | Registered: May 2002 | IP: Logged | spasman Very Prolific Member Member # 12277 posted 08-21-2004 09:25 PM -------------------------------------------------------------------------------- http://www.gastro.org/clinicalRes/brochures/ibs.html Colon motility (contraction of intestinal muscles and movement of its contents) is controlled by nerves and hormones and by electrical activity in the colon muscle. The electrical activity serves as a "pacemaker" similar to the mechanism that controls heart function.
 

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Discussion Starter · #17 ·
MY RESEARCH STARTED WITH THIS ABSTACT: http://www.bioscience.org/2003/v8/b/989/fulltext.htm Frontiers in Bioscience 8, b1-5, January 1, 2003] COLONIC PACING IN THE TREATMENT OF PATIENTS WITH IRRITABLE BOWEL SYNDROME: TECHNIQUE AND RESULTS Ahmed Shafik 1, Olfat El-Sibai 2, Ali A. Shafik 3, Ismail Ahmed 3 1 Professor and Chairman, Department of Surgery and Experimental Research, Faculty of Medicine, Cairo University, Cairo, 2 Professor and Chairman, Department of Surgery, Faculty of Medicine, Menoufia University, Shebin El-Kom, 3Lecturer in Surgery, Department of Surgery and Experimental Research, Faculty of Medicine, Cairo University, Cairo, Egypt TABLE OF CONTENTS 1. Abstract 2. Introduction 3. Material and methods 3.1. Subjects 3.2. Methods 3.2.1. Pacemaker application 3.2.2. Determination of the myoelectric activity: basal and during pacing 3.2.3. Home pacing4. Results and Discussion 4.1. Effect of colonic pacing on the clinical manifestations of the IBS 5. Acknowledgment 6. References 1. ABSTRACT The treatment of the irritable bowel syndrome (IBS) is not entirely satisfactory as the exact cause of the condition has not been revealed. We have demonstrated in a recent study that the IBS exhibited a "tachyarrhythmic" electromyographic pattern; the wave rhythm was irregular and wave variables were higher than those of the healthy volunteers. We suggested that a disorder of the colonic pacemaker discharges these abnormal waves thereby causing the motor disorders of IBS. In another study, we determined the colonic pacing parameters needed to modulate the disordered pacemaker. In the current communication we investigated the effect of colonic pacing, using these parameters, on the EMG activity of the sigmoid colon (SC) and on the clinical manifestations of patients with IBS. A pacemaker was implanted in a subcutaneous pocket in the inguinal area and its two leads were hooked to the colosigmoid junction. The effect of colonic pacing on the SC EMG activity was investigated by inserting two recording electrodes into the SC muscle. The patients were then trained for home pacing after removal of the 2 recording electrodes. Nine patients (age 42.7�4.2 years, 6 women) with IBS were studied. The pre-pacing tachyarrhythmic pattern of EMG was recorded. On colonic pacing, the slow wave rhythm became regular and wave variables were normalized; the symptoms of the IBS improved. The optimal parameters used for pacing comprised an amplitude of 6 mA, a pulse width of 150 ms and a frequency of 25% higher than that of the basal colonic waves. In 7/9 patients the improvement of symptoms continued when pacing was ceased after 6 months of daily pacing; the pacemaker was removed after 3 months of non-pacing. In 2/9 patients, pacing needed to be continued because the symptoms recurred each time the pacing was ceased. In conclusion, colonic pacing succeeded in normalizing the tachyarrhythmic pattern and relieving the symptoms of the IBS. No complications were encountered and the method was well accepted and tolerated. Further studies on a large group of patients are required.--------------------------------------------------------------------------------From: canada | Registered: May 2002 | IP: Logged | spasman Very Prolific Member Member # 12277 posted 08-21-2004 08:37 PM --------------------------------------------------------------------------------IS THERE ANYONE WHO KNOWS WHICH COMPANY SELL THE COLONIC PACEMAKER?I THINK I NEED AN ELECTRICITY modulator.--------------------------------------------------------------------------------From: canada | Registered: May 2002 | IP: Logged | spasman Very Prolific Member Member # 12277 posted 08-21-2004 09:09 PM -------------------------------------------------------------------------------- http://bioinformatics.weizmann.ac.il:3456/...8/b/989/pdf.pdf --------------------------------------------------------------------------------From: canada | Registered: May 2002 | IP: Logged | spasman Very Prolific Member Member # 12277 posted 08-21-2004 09:25 PM -------------------------------------------------------------------------------- http://www.gastro.org/clinicalRes/brochures/ibs.html Colon motility (contraction of intestinal muscles and movement of its contents) is controlled by nerves and hormones and by electrical activity in the colon muscle. The electrical activity serves as a "pacemaker" similar to the mechanism that controls heart function.
 

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Discussion Starter · #18 ·
I CANT BELEIVE THE RESULTS OF THE RESEARCH ABOVE.
 

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Discussion Starter · #19 ·
I CANT BELEIVE THE RESULTS OF THE RESEARCH ABOVE.
 

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Discussion Starter · #20 ·
Here an abstract from Mayo clinic.They talk about the myoelectric activity of IBSers.I wonder what is this.Quote:pathophysiologyThere is increasing evidence that people with IBS have abnormalities in their colonic myoelectric activity and response to stimuli.24 Cholecystokinin, cholinergic drugs, and morphine increase colonic contractions in patients with IBS, whereas in normal persons these stimulants alter spike activity.It was a quote from Mayo clinic MD's. http://www.familypractice.com/references/r...Bowel/bowel.htm ***I suspect that Morphine works.I have tried it one time and the motility instantly stop the spams.I want to try it at low dose.Anyway,NSaids and Codeine have nasty side effects.
 
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