Hi BJ, Good Topic. MEDICATION. I havent heard about any of that. I use to take Donnatal when I was having alot of difficulty 2 years ago. I personally dont think trying all this meds is a great idea when i feel that most of us can probably do without. I dont know your situation but I do know that I Have had IBS_D with colitis for 17 years and have pretty much cured myself on my own. A little bit of research and just taking time for me worked. My best advise is todo the same. Sorry I coudnt help with the meds but just thought I would give you some strength to try to move on and get beyond the meds. Good luck BJ