I asked my GI if the pill could have caused my more frequent spasms from IBS. She said that it is fairly common for IBS to act up with the pill-due to the increase in your hormones and it affects IBS somehow///// Stopped the pill and didn't have it as bad. BUt, it's hard to tell what's actually causing the spasms when you have IBS. Sometimes it seems like hormones, sometimes food, stress, etc. It's hard to say-I may have just been having a bad flare-up of IBS those couple of months. Still get the occasional sharp pains......And always will unfortunately.