First off, I am so glad I found something like this. For the past year I have been suffering with IBS-D and it's really killing me. Every time I have to go to work in the morning it's so hard for me to just get out without having to go to the bathroom at least three times before I leave the house (and two immodiums later). I live on immodium and would not dare to go anywhere without it. I went for a colonoscopy this past july and he found nothing out of the ordinary and wanted me to eat more fiber. Gee that didn't help at all. Can anyone tell me what medication is out there to help me live a normal life and not have to worry about if I am going to make it to work and make it all day at work without an attack. Thank you.