Hello to all. I am a new member. I'm hoping to fing some experienced input into my current worries and confusion. I have been diagnosed with Collagenous Colitis (after a few years with an IBS diagnosis). Collagenous Colitis is often called microscopic colitis because the colon can look normal under colonoscopy until the doctor takes a biopsy in one of the correct places and then an extra band of collagen is detected under the microscope. It's a diagnosis many IBS sufferers can eventually come to. I have had this condition for ten years now. Here's my concern. Since I managed this mainly with diet for ten years, and realizing how long it has been, I began to worry that maybe I was causing myself harm due to the long term ongoing inflamation and diarrhea ( I do have periods of less intense 'activity' and even weeks, and a few times a month, with normal bms. I have never had blood in my stool over these years). So I visited my doctor and thought I'd TRY a drug. I was given sulphasalazine, 500mg 2x a day. For the first three weeks all was ok, and I even began to have 'normal' bms. Then, about three weeks in, about an hour after eating lunch,I had a severe gripping sort of pain in my lower abdominal area- (around the belly button area). It lasted for two hours. I had lots of gas- (belching, and flatulance) and a distended abdomen ( I had actually woken up that am with a bloated abdomen, which remained bloated even after two bowel movements). I saw a pharmacist who gave me Oval for gas- around 1/2 hour after taking it, the severe abdominal discomfort went away ( I was belching and had flatulance-all of which relieved it). Then followed three days of nausea, anorexia (I couldn't eat), and lots of gas, and vague abdominal pains - (though not severe or excessive at all). I continued to have regular bowel movements though they appeared 'thinner' than previously. Then It occured to me that maybe this was a drug side effect. So a google search revealed that, indeed, all of these symptoms matched described sulphasalazine side effects, so I discontinued the drug. Another week followed, before all symptoms had subsided. My diarrhea returned. Now here's my worry: WAS that the drug- the 'side effects' lasted longer then they should have, didn't they? Was it something ELSE and not drug side effects. I keep thinking od scary things. I woud greatly appreciate thoughts and input on this. Thankyou so much in advance.