I have recently dicovered this BB and am happy to know that there is support out there for IBS sufferers. I am a 29 year old woman who is trying very hard to maintain an active, normal life in NYC. I have had IBS-D for many years and it has become increasingly difficult in the past year. As a result (I think) I have started feeling increasingly anxious and am contemplating taking Paxil. I have read about Lotronex and am guardedly hopeful about its prospects. In the meantime, I am hoping that someone might have a good gastroenterologist recommendation in manhattan. I have been so dissapointed with the doctors I have seen. Also - any info on experiences with Paxil?Thanks.