Lately (last few weeks in particular) I have found that I feel totally 'wiped out' after I have a bout of D during the day. It can be anytime of day, but often in the morning. I used to recover more quickly from an increase in my symptoms that might last one or two weeks, but I don't seem to be in recovery mode as much lately, rather it has become more of a daily drag. Is my IBS getting worse, and why do I feel so drained after a loose BM? I have tried all the usual remedies which seem to improve my symptoms for a while and then I'm back to square one. I will be seeing the GI specialist in two weeks for the first time in a year. Not sure what he will do at this juncture. I have had 2 negative colonoscopies (last one almost 3 or 4 yrs ago). My mother suffers from colitis (non ulcerative) and my aunt had fairly severe Crohn's. I worry that my IBS could lead to IBD - (apparently no evidence to prove that one can lead to the other), or even worse, my most dreaded thought - colon cancer. I have lost about 3 pounds (I only weigh about 119 lbs) and I am 5 feet 6 inches. Every article I read scares me, but I just want to feel better, and I am at a loss as what to eat. I have not been prescribed any meds, just use occasional immodium and metamucil. Perhaps my doctor will try a prescription med. I do take caltrate daily as I need calcium as well, but not sure it helps the IBS.Any suggestions or thoughts would be appreciated. Also, is the feeling of being 'wiped out' common with other sufferers of IBS?I