Rowe thanks, yes I have spent a lot of time for sure, and I did this because I had to know what was wrong with me personally and get serious about it. Really they know this about IBS and that is there is a brain gut problem going on that causes the symptoms.I to was tired of them telling me it was in my head and now I hate that term (from drs or people) and I don't believe anymore any doctor would say that who has any knowledge about IBS and if they did I would run out the door. But if they say its is both, then they know more about what they are talking about.I am very sorry about your husband.The drug you took helped because of the serotonin connection and IBS, those drugs help to block pain signals to the brain and at the same time reduce anxiety which effects the gut feedback loop.As far as pain and IBS is concerned, I had to really learn what was causing it, because I was not really treating it effectively because I did not understand it.I hope also you can get some sleep soon, lack of sleep is a big trigger to IBS.have you been on this drug long?