Last time after 2 trips to the emergency room after the super bowl I wrote that I started taking colenetix and had relief from the cramping within a day, what I didn't write was I had been taking calcium and acidophilus before that since it wasn't working. As the months went buy I ran out of everything, but I figured I was cured, the first thing that happened was my back, shoulder arms and hand really started to ache, I wound up going to the doctor he told me it was arthritis, which I thought was weird because I have had arthritis for 30 years and it had never bothered me that much, then it dawned on me that the calcium was controlling my arthritis so I started it again, but then I started to get the stomach cramps and diarrhea again, I started the colonetix again, but the pain was gradually increasing, Saturday morning I went out and brought some more acidophilus, but I didn't want to take it with the first stage of the colenitx, because I thought it might be canceled out, by the afternoon I was in so much pain I couldn't even sit up, I then the vomiting started, I took the probiotic then got dressed to go to the emergency room, but when I but on my jeans the presssure from then around my waist give me enough relief that I started to wait it out, then about an hour later the pain was gone, then it hit me that it was the combination of Colonetix, calcium and acidophilus that worked for me