I have IBS-D I have had IBS for my entire life in one form or another and have known I have had it for over a decade now.I am on a series of meds to cut down on the D, to cut down on the pain and to cut down on the sickness.I am never able to gain weight and i often feel most of my pain could be linked to me having a very very low BMI but i cant really prove that.The meds I am on at the moment I take 4 times a day, each time I take 10mg Amitriptyline, 135mg Mebeverine, occasionally 10mg motilium for sickness and 2.024Grams of Ibsacol.I frequently take Loperamide between 3 and 10 tabs usually and though my doctor refuses to prescribe me more if i have a real problem Immodium plus is the only thing which can stop the D and sometimes the pain. Quite frequently however I have really bad stomac pains which have nothing to do with anything that I am aware of, even if I am not hungry sometimes eating some food can relax the pain for a short period of time though its more painful while I am eating.when i have D i know that the pain is more likely to go away that not by having some anti-dietetics. infact I used to presume that it would be on its way and thus took some to stop it before it started. but now I am just getting the same intense pains when i have no other symptoms and I have no idea what can help.Any ideas of what to try, heat and sleep help but hard to do those when your not in the house by yourself lol