Relic, I have pain on my right side under my ribs, basically along the ascending colon line, almost constantly. I have been given every test imaginable: I have had a laparoscopy,colonoscopy and gastroscopy AND biopsy, and an lower G.I. series as well as a retrograde for stones, 2 u'/s (one pelvic) and 3 CT scans! So far, all they can say is it is IBS-C and I have been put on miralax. I try gas-x every now and then to see if it worksm, and sometimes it helps. I also try using glycerin suppsoitories, even though I go regularly, I seem to never completely empty. This helps the pain a little.I'm try to get pregnant right now, but when I know I'm not pregnat I will take xanax pretty regularly, and that seems to help. I have tried every external stress reduction I can think of. I am thinking of acupuncture next! Have you tried this?