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Please help me.I took an antibiotic in May for a sinus infection, and two weeks later I had a suuden onset of diarrhea. Seven weeks later and the doctors still dont know what to do. I have lost around 30 pounds and still losing. The tests they have performed are stool specimens all came back negative. Blood tests showed nothing twice. Gall bladder ultrasound, mine is great shape. Cat Scan which showed nothing out of the ordinary. And finally today a colonoscopy and EGD which revealed everything is looks great. My primary care tried Flagyl orally but I could not tolerate it, the pain sent to to the ER. I have taken Align probiotics and eaten tons of yogurt and tried peppermint oil. Most food intolerances are ruled since I dont eat much these days. If anyone has any thoughts or suggestion I would be most apprecitive since my doctor is scratching her head and saying "wow I cant believe this!"
 

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You might try reading the Calcium thread, and have you tried Imodium?Some people can get a bile imbalance (release more bile than they can recycle so even if the gall bladder was normal (and sometimes they don't check for "too much" as usually they are looking for "can't release any" it may be worth trying a Bile Binder like Questran. It is generally constipating anyway, and if there is some excess bile it binds that up.There is a New England Journal of Medicine review from back about 2001 that has doses for the Questran and Imodium if your doc wants to look it up.There is a recent study that showed some IBS-D types do well on a low carb diet. You would just need to make sure your portion sizes are high enough to maintain weight.FWIW starving as long as possible only makes the diarrhea and pain worse when you finally do eat. Much better to eat 300 calorie mini meals every 3 hours or so than not eat all day and then try to play catch up with dinner.
 

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Fon: I think they need to run the stool tests again and perhaps at a better lab. Maybe even go to a different GI specialist or teaching hospital if you can!!! This is NOT your run of the mill IBS-D. I had similar issues and actually needed ANOTHER antibiotic called Tetracycline to make me better. I am just worred that you may have c-dif and it was missed. If that is the case, you may need to be in the hospital on IV antibiotics depending on the strain. On the other hand, if the sinus infection antibiotic caused too much die-off of your good bacteria, it is possible that bad bacteria overgrew. Your case demands a better doctor and better institution. A loss of 40 pounds is very scary. That is what happened to me and by the time they finally figured it out, or should I say, were ready to try anything, I had dropped below a size 2. I am five foot nine and normally wear a 10 (female). My prayers to you that they find something out very soon. Any doctor that thinks weight loss is common to IBS is wrong. It also can take up to FIVE consecutive stool samples for a proper analysis. I know you feel horrible but be your own best advocate and demand another and better round of stool tests! That is just my layperson's opinion.
 
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