I have read a lot of postings from those of you taking Immodium. Might I suggest you talk to your doctors ### Prilosec? I have used it for extended periods of time w/ no side affects. Normally it is prescribed for acid reflux, but my regular doctor prescribed it for me because I had D so bad that I lost 30lbs in 1 month! It was miraculous! I haven't had any drug interactions and now I only use it when absolutely necessary. BTW 1 capsule last for 24 hours. so you only need it once a day. Also, w/ it I can eat anything I want.Another thing before I forget, I want to thank those of you who have suggested Caltrate. It has worked wonders. the first 2 days I used it in conjunction w/ prilosec and now i'm back to "normal" I'm just taking the caltrate now and experienced some gas but phazyme has solved that problem as well. I hope this has been helpful. You might want to give it a try ask your doctor. Good Luck!