I've tried all the expensive acidophilus from Health Food stores, some at almost $100 for just 30, and I now take Culturelle, otc, at justabout $22 for 30, and find them the best.Love them. They are also so strong they cantravel, useful when I went to France recently,but I do keep them in the fridge to help thembe more potent longer.I also take 2 digestive enzymes with my meals.I have Crohn's, mild, not typical and am drug free except for above and calcium, multi-vits andan elimination diet I stick to, even thoughin remission.OO