prucalopride, coming out in Europe!

yes zeppod--you're right. some--but not all--docs are really cautious about that--they won't write a script for a drug that's not fda approved.but some will. going way back to zelnorm was first approved--it was first approved in switzerland i think (that's where novartis is based) and i think other parts of europe as well--i can't remember exactly where-- but i do remember how excited everyone here on the c board and the c drugs board was--tons of posts-- and people were asking their docs for scripts so they could get it from overseas pharmacies that had it. and what we found out was some docs wouldn't write the scripts because zelnorm wasn't fda approved but thankfully there were some docs who would. and those lucky people who were able to get a script sent them in to the overseas pharmacy to get it. i can't remember any of the pharmacy names but i know there was one in particular in switzerland that people were getting zelnorm from before it finally was approved here. and also i suppose it's always possible that resolor will show up at medsmex or inhouse pharmacy before it's approved here in the usa so maybe we have a chance of getting it from one of these no-script-required pharmacies. as of yet, neither medsmex nor inhouse has resolor but i'll keep checking them periodically.

well apparently it worked well enough in the clinical trials:In clinical studies, the efficacy of prucalopride was established in three multicentre, randomised, double-blind, 12-week placebo controlled studies in subjects with chronic constipation.About PrucalopridePrucalopride has been tested in 2,752 patients (including elderly) in double-blind randomized placebo-controlled studies up to 12 weeks of treatment, including three identically designed pivotal phase III studies with patients presenting an average history of 20 years of chronic constipation.In contrast to laxatives, prucalopride triggers a physiological and peristaltic reflex in the colon through stimulation of the 5HT4-receptors on the intramural nerves. This accelerates overall transit along the GI tract, induces colonic mass movement and significantly enhances colonic emptying. Prucalopride stimulates bowel function by specifically targeting the underlying impaired motility. http://www.movetis.com/journalists/press-r...urce=journalist http://www.movetis.com/products/resolor-prucaloprideand hopefully early next year we'll be able to find out more when people start to post their own experiences with it.