My doctor has taken me from 75 mg down to 37.5 mg to see if that keeps my blood pressure lower. Seems to be working as far as the BP goes, but I am telling you - I am so wired I could fly off the walls. I want to talk incessantly, my thoughts race through my head, and I just feel edgy. I don't feel like I'm on the verge of a panic attack, just spazzed out, I guess.Could this be withdrawal from Effexor 75 mg? Lord, I'd hate to think what I might be like if I go off it completely. I have been obsessing a lot lately, too. Not a good thing.