Floyd,The diphenoxylate, otherwise known as Lomotil, can be habit forming in that it contains opium; or, at least that's what the doc and pharmacist said. Yes, you can also build a tolerance to it. It works so well, I had started taking it daily, "just in case". Well, that was 14 years ago. When all this started I was taking one a day. Now, I can usually get by on 4 a day, although the script reads I'm allowed 8 a day. The doc (GI) believes I've not had to go higher over the years due to taking the Tranxene and Remeron. Who knows? But, unlike you, I hate taking meds yet would never suggest that once you start you try to stop this one abruptly. It is not a pretty picture of "climbing the walls", nausea, blah, blah, blah. The amount you take would have to be reduced very gradually. Personally, I love it but believe also, that as soon as I quit working, I should be able to wean off all meds except the calcium supplement.You're right about the stress, too. Who knows why we got to be the lucky recipients of this condition and, while I detest dealing with it and having to think about it, I do thank God I can still see, walk, talk, smell, touch, taste, etc. This is without question a profoundly debilitating illness which annoys me to death that it doesn't qualify for disability, but when I think of the alternatives...well, I guess things COULD be worse.In any case, "knock your socks off" with Lomotil !! If you're like some of us, you'll think you've captured your life back...others have reported no positive effects for them.Best wishes..Godspeed...